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Isolation and Identification of Flavone Aglycones in Roots of Desmostachya bipinnata Stapf

By: Rahate, Kalpana P.
Contributor(s): Rajasekaran, A.
Publisher: Mumbai Indian Journal of Pharmaceutical Science 2018Edition: Vol. 80(03), September-October 1.Description: 551-556.Subject(s): PHARMACEUTICS | Apigenin | Luteolin | QuercetinOnline resources: Click here In: Indian journal of pharmaceutical sciencesSummary: Roots of Desmostachya bipinnata Stapf are used in the treatment of jaundice and asthma in Indian traditional medicine. Phytochemical investigation of the methanol extract of the roots of this plant led to isolation of three flavonols. The structures of these compounds were assigned on the basis of elemental analysis and spectroscopic evidences as apigenin, luteolin and quercetin, of which apigenin and luteolin were isolated for the first time. The yield of these compounds was 0.0034, 0.0026 and 0.0042 % w/w, respectively. These findings suggested the possibility that the three flavonoids isolated from the roots of Desmostachya bipinnata could be responsible for the benefits to human health offered by these roots.
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Roots of Desmostachya bipinnata Stapf are used in the treatment of jaundice and asthma in Indian traditional medicine. Phytochemical investigation of the methanol extract of the roots of this plant led to isolation of three flavonols. The structures of these compounds were assigned on the basis of elemental analysis and spectroscopic evidences as apigenin, luteolin and quercetin, of which apigenin and luteolin were isolated for the first time. The yield of these compounds was 0.0034, 0.0026 and 0.0042 % w/w, respectively. These findings suggested the possibility that the three flavonoids isolated from the roots of Desmostachya bipinnata could be responsible for the benefits to human health offered by these roots.

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